what should i do? can i move the program to my E,drive?it has more room for storage there,and will it work there?

I'd suggest to let your program be on the main drive, but you can move your models to another, external drive, if there will be such a need.
On the GUI in Settings _ Advanced _ Software options is an option: Change the Storage Folder.

How to use it right, check this link:

http://www.virtuagirl.com/forumPost.php?foId=39&ftId=22758

Уголок новых участников / Virtuagirl Storage

I am grateful that I am able to store the private shows on a portable drive. It's great that you can download the private shows on your computer but I found that my hardrive filled up. Being able to s...

Or make a Search: Storage (within All Sections), and you can find a lot of useful info about.